Abstract Background Somatic copy number alternation (SCNA) is a common feature of the cancer genome and is associated with cancer etiology and prognosis.The allele-specific SCNA analysis of a tumor sample aims to identify the allele-specific copy numbers of both alleles, adjusting for the ploidy and the tumor purity.Next generation sequencing platf
In multiple myeloma, focal lesions, as well as diffuse and variegated infiltration patterns, can be detected by magnetic resonance imaging.In the Wax current study, we compared treatment response in 100 myeloma patients with changes in infiltration patterns in whole Homewares body magnetic resonance imaging before and after autologous stem cell tra
In this paper, we present a multi-scale co-affection model of HIV infection and opioid addiction.The population scale epidemiological model is linked to the within-host model which describes the HIV and opioid dynamics in a co-affected individual.CD4 cells and viral load data obtained from morphine addicted SIV-infected monkeys are used to validate
In this paper, we present a multi-scale co-affection model of HIV infection and opioid addiction.The population scale epidemiological model is linked to the within-host model which describes the HIV and opioid dynamics in a co-affected individual.CD4 cells and viral load data obtained from morphine addicted SIV-infected monkeys are used to validate